NCT00064753intervention×1 — no declared intervention names biotinclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT02936037intervention×1 — no declared intervention names biotinclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT06605768intervention×1 — no declared intervention names biotinclinicaltrials.gov intr search: query.intr=biotin2026-10-13
PMID:10720289cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:11078767cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:12221157cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:12504397cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:15090564cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:15451222cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:15557491cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:17262850cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:19233038cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:19847908cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:20621711cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:21975206cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:22714021cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:23535489cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:24485135cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:24871874cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:25278115cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:25935887cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:32669900cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:9820296cited by PMID:27589059; not about the subject it would be filed undercited by PMID:27589059; its own chemicals/MeSH/title name no enrolled subject2026-10-20
PMID:11975567cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:15330631cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:15548086cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:16407987cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:17175580cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:17406607cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:17942682cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:18272492cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:18451302cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:19104067cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:19714693cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:20080615cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:20187640cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:20192265cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:20309487cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:20489181cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:21062072cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
PMID:8589427cited by PMID:21761519; not about the subject it would be filed undercited by PMID:21761519; its own chemicals/MeSH/title name no enrolled subject2026-10-25
Discarded — another reason, stated per paper21 papers
PMID:11870507no claim extracted — cause not determined — DOSED: yttrium-90-biotin radioconjugate in a three-step avidin-biotin pretargeting regimen, abstract | Yttrium-90-labelled biotin delivered by three-step avidin-biotin pretargeting radioimmunotherapy, abstractpipeline:batch2026-10-12
PMID:24812013no claim extracted — cause not determined (one pass only) — measured: brain MRI lesion signal abnormality resolution, descriptive lesion location and extentpipeline:batch2026-10-12
PMID:29808469no claim extracted — cause not determined (one pass only) — measured: visual acuity change, logMAR at 100% contrast (selected eye)pipeline:batch2026-10-12
NCT02483000design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT00731588design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT01204216design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT01474486design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT02757898design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT02967679design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT03364686design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT04223232design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT04426591design×1 — allocation NA -- not randomisedclinicaltrials.gov intr search: query.intr=biotin2026-10-13
NCT04476277design×1 — allocation NON_RANDOMIZED -- not randomisedclinicaltrials.gov intr search: query.intr=biotin2026-10-13
PMID:17186472no claim extracted — subject_absent — DOSED: Paper is about coenzyme Q10 deficiency and PDSS2 mutations in an infant with Leigh syndrome; biotin is never mentioned | Nothing dosed; paper is a case description of PDSS2 mutations and coenzyme Q10 deficiency in an infant with Leigh syndrome. Biotin is not mentioned.pipeline:batch2026-10-23
PMID:32445355no claim extracted — cause not determinedpipeline:batch2026-10-23
PMID:26715368no claim extracted — cause not determinedpipeline:batch2026-10-23
PMID:28222020no claim extracted — cause not determined (one pass only) — measured: analytical interference of high-dose biotin on streptavidin-biotin hormone immunoassays, results before versus after N5 biotin removalpipeline:batch2026-10-23
PMID:7726384no claim extracted — cause not determined (one pass only) — measured: maintenance of normal neurologic function (unscored, narrative) in biotinidase, holocarboxylase synthetase deficiency and Leigh encephalopathypipeline:batch2026-10-23
PMID:21761519no claim extracted — cause not determinedpipeline:batch2026-10-25
PMID:9015339no claim extracted — subject_absent — DOSED: Abstract never mentions biotin; it is about vestibular compensation, Fos expression and flocculectomy in rats | Paper is about vestibular compensation in rats (labyrinthectomy, flocculectomy, retrograde tracing); abstract never mentions biotinpipeline:batch2026-10-25
Discarded — an endpoint this vocabulary does not hold16 papers
PMID:32557122no claim extracted — no_outcome_node — measured: time to first clinical relapse in multiple sclerosis, Cox hazard ratio after propensity matching | time to first clinical relapse in progressive multiple sclerosis, Cox hazard ratio with propensity-score matchingpipeline:batch2026-10-12
PMID:32964402no claim extracted — no_outcome_node — measured: annualized relapse rate in multiple sclerosis, Poisson regression with IPTW propensity adjustment | annualized relapse rate in progressive multiple sclerosis, Poisson regression with IPTW propensity scorepipeline:batch2026-10-12
PMID:10075337no claim extracted — no_outcome_node — measured: 24-hour urinary recovery of biotin and biotin metabolites by HPLC avidin-binding assay (bioavailability) | urinary recovery of biotin and biotin metabolites over 24 h, HPLC avidin-binding assay (bioavailability)pipeline:batch2026-10-23
PMID:22791079no claim extracted — no_outcome_node — measured: muscle cramp onset and severity in hemodialysis patients, no instrument stated | muscle cramp onset and severity in hemodialysis patients, patient-reportedpipeline:batch2026-10-23
PMID:31344296no claim extracted — no_outcome_node — measured: Onychodystrophy Global Severity Score (OGSS), nail dystrophy, splitting, dyschromia and pitting composite | Onychodystrophy Global Severity Score (OGSS), clinician-assessed nail dystrophy, splitting, dyschromia and pittingpipeline:batch2026-10-23
PMID:33222767no claim extracted — no_outcome_node — measured: composite responder proportion, confirmed improvement in EDSS or timed 25-foot walk (TW25) at month 12 confirmed at month 15pipeline:batch2026-10-23
PMID:33928390no claim extracted — no_outcome_node — measured: proportion of inpatient encounters with biotin-susceptible immunoassay testing, retrospective chart review | count of biotin-interference-susceptible immunoassays performed in inpatients receiving high-dose biotin, retrospective chart reviewpipeline:batch2026-10-23
PMID:40914826no claim extracted — no_outcome_node — measured: incident all-cause dementia and Alzheimer's disease, algorithmically defined outcomespipeline:batch2026-10-23
PMID:7840079no claim extracted — no_outcome_node — measured: lymphocyte propionyl CoA carboxylase and pyruvate carboxylase activity; plasma biotin concentration | lymphocyte propionyl CoA carboxylase and pyruvate carboxylase activity; plasma biotin concentration (method not stated)pipeline:batch2026-10-23
PMID:16773504no claim extracted — no_outcome_node — measured: seizure frequency and urinary organic acid excretion in a single patient with 3-methylcrotonyl-CoA carboxylase deficiency, urine analysis | seizure frequency in a single case report; urinary organic aciduria (3-methylcrotonylglycine, 3-hydroxyisovaleric acid)pipeline:batch2026-10-23
PMID:23269594no claim extracted — no_outcome_node — measured: clinical and neuroradiologic improvement in biotin-responsive basal ganglia disease, descriptive case series, no scale named | clinical and neuroradiologic improvement (unscored, narrative) in biotin-responsive basal ganglia diseasepipeline:batch2026-10-23
PMID:9128289no claim extracted — no_outcome_node — measured: lymphocyte mitochondrial carboxylase activity and urinary organic acid excretion in multiple carboxylase deficiency, enzyme assay and organic acid profile | mitochondrial carboxylase activity in lymphocytes and fibroblasts; urinary organic acid excretion; clinical symptom resolution at 10-100 mg biotin/dpipeline:batch2026-10-23
PMID:8232780no claim extracted — no_outcome_node — measured: cerebral atrophy on serial CT-scan and MRI brain imaging, two-patient case report | brain atrophy on serial CT/MRI imaging (case report)pipeline:batch2026-10-25
PMID:8352834no claim extracted — no_outcome_node — measured: flash-evoked visual potentials, neuro-ophthalmological and motor deficit recovery in a single-patient case report | flash-evoked visual potentials, neurophysiological recording (single case)pipeline:batch2026-10-25
PMID:8477615no claim extracted — no_outcome_node — measured: subjective clinical improvement in brittle nails (proportion improved), retrospective patient evaluation | brittle nails, subjective clinical improvement proportion (retrospective, no instrument)pipeline:batch2026-10-25
PMID:23089740no PMID parsed, abstract under 200 characters, or no record returned by efetchcited by PMID:27589059; efetch/papersFor returned no usable record2026-10-20
PMID:25200713no PMID parsed, abstract under 200 characters, or no record returned by efetchcited by PMID:27589059; efetch/papersFor returned no usable record2026-10-20
PMID:12203546no PMID parsed, abstract under 200 characters, or no record returned by efetchcited by PMID:21761519; efetch/papersFor returned no usable record2026-10-25
PMID:17506567no PMID parsed, abstract under 200 characters, or no record returned by efetchcited by PMID:21761519; efetch/papersFor returned no usable record2026-10-25