biotin/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on serious adverse event incidence
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Synthesized data on incidence of any AEs (RR 0.98; 95% CI 0.92-1.04; 3 trials; I2 = 0%) [high COE] and any serious AEs (RR 0.98; 95% CI 0.77-1.24; 3 trials; 889 participants; I2 = 0%) [moderate COE] were not significantly different between HDB and placebo groups.”
Quoted verbatim from High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials.. - Study
- meta-analysis
- Participants
- 889
- Dose
- high-dose biotin at least 300 mg/day for at least three months
- Population
- Adults with multiple sclerosis (mostly progressive); three pooled randomized trials of oral high-dose biotin (at least 300 mg/day) as adjunctive treatment versus placebo
Effect 0.98 risk ratio, 95% CI 0.77 to 1.24
High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials.2021PMID:34332461Permalink
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To cite this finding: https://catalystproject.ai/e/01M5MDHGQPH5QY7CKAPHY9A14Z