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Proteins/UNIPROT:Q969W1
Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6. Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization (By similarity). Also required for eye development (By similarity). Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function. May play a role in DNA damage response (By similarity). May be involved in apoptosis regulation (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity)..
Function from UniProtKB (Q969W1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
61 statements
61 statements · 3 reference databases · Subject: ZDHHC16 · Sources: Bgee, Hetionet, Rhea
1 reaction
L-cysteinyl-[protein]+hexadecanoyl-CoAS-hexadecanoyl-L-cysteinyl-[protein]+coenzyme A(4-)
Catalysed by ZDHHC11B or GLUL or ZDHHC20 or ZDHHC24 or ZDHHC13 or ZDHHC17 or ZDHHC21 or ZDHHC23 or ZDHHC14 or ZDHHC22 or ZDHHC1 or ZDHHC19 and 13 more alternatives
Reaction pageLeft to rightBalance undeterminable
4 names
Resolves to: ZDHHC16
Rhea RHEA:36683CC BY 4.0Reference data