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Proteins/UNIPROT:Q8NBN3
Voltage- and pH-dependent, inwardly rectifying cation channel that mediates ion flux across the Golgi membrane, supporting luminal acidification necessary for normal Golgi morphology and function. Implicated in normal touch sensitivity through the generation of mechanically activated currents. Could also be involved in cell mechanosensitivity regulating cell adhesion and migration. May also be involved in retrograde transport from endosomes to the trans-Golgi network (TGN). Contributes to hippocampal spatial and contextual memory by maintaining Golgi function and structural integrity in hippocampal neurons (By similarity)..
Function from UniProtKB (Q8NBN3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 2 · transported by
2 compounds
2 compounds.
0 reported routes2 assembled routes
92 statements
92 statements · 6 reference databases · Subject: TMEM87A · Sources: Bgee, Hetionet, Human Protein Atlas, Reactome, Rhea, WikiPathways
3 reactions
3 names
Resolves to: TMEM87A
Transported by ANO9 or HTR3E or TMEM150C or KCNK1 or KCNK3 or GRIN2D or GRID2 or KCNQ3 or KCNQ2 or GRIN3B or HCN1 or TRPA1 and 98 more alternatives
Reaction pageRight to leftBalanced
Rhea RHEA:34963CC BY 4.0Reference data