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Proteins/UNIPROT:Q15573

TAF1A

Protein·UNIPROT:Q15573

Open in the graph

Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits..

Function from UniProtKB (Q15573), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

familial isolated dilated cardiomyopathy has a germline basis in TAF1ADiseaseGenCC HGNC:11532|MONDO:0700335Inferred only

Statements

54 statements

54 statements · 4 reference databases · Subject: TAF1A · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Search this listOrder

TAF1A covaries with FSIP2ProteinHetionet hetionet:covaries:401024-9015Inferred only
ANP32A interacts with TAF1AProteinHetionet hetionet:interacts:8125-9015Inferred only
ESR1 interacts with TAF1AProteinHetionet hetionet:interacts:2099-9015Inferred only
H2AC20 interacts with TAF1AProteinHetionet hetionet:interacts:8338-9015Inferred only
H2BC21 interacts with TAF1AProteinHetionet hetionet:interacts:8349-9015Inferred only
H3-4 interacts with TAF1AProteinHetionet hetionet:interacts:8290-9015Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with TAF1AProteinHetionet hetionet:interacts:8356-9015Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with TAF1AProteinHetionet hetionet:interacts:8968-9015Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with TAF1AProteinHetionet hetionet:interacts:8354-9015Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with TAF1AProteinHetionet hetionet:interacts:8351-9015Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with TAF1AProteinHetionet hetionet:interacts:8353-9015Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with TAF1AProteinHetionet hetionet:interacts:8357-9015Inferred only

Show the remaining 42

H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with TAF1AProteinHetionet hetionet:interacts:8355-9015Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with TAF1AProteinHetionet hetionet:interacts:8350-9015Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with TAF1AProteinHetionet hetionet:interacts:8352-9015Inferred only
H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 interacts with TAF1AProteinHetionet hetionet:interacts:8358-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8367-9015Inferred only
TAF1A interacts with H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16ProteinHetionet hetionet:interacts:121504-9015Inferred only
TAF1A interacts with H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16ProteinHetionet hetionet:interacts:554313-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8359-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8294-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8360-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8364-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8363-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8361-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8365-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8362-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8366-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8368-9015Inferred only
H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 interacts with TAF1AProteinHetionet hetionet:interacts:8370-9015Inferred only
TAF1A interacts with POLR1GProteinHetionet hetionet:interacts:10849-9015Inferred only
TAF1A interacts with RRN3ProteinHetionet hetionet:interacts:54700-9015Inferred only
RUNX2 interacts with TAF1AProteinHetionet hetionet:interacts:860-9015Inferred only
SET interacts with TAF1AProteinHetionet hetionet:interacts:6418-9015Inferred only
TAF12 interacts with TAF1AProteinHetionet hetionet:interacts:6883-9015Inferred only
TAF1B interacts with TAF1AProteinHetionet hetionet:interacts:9014-9015Inferred only
TAF1A interacts with TAF1DProteinHetionet hetionet:interacts:79101-9015Inferred only
TBP interacts with TAF1AProteinHetionet hetionet:interacts:6908-9015Inferred only
TP53 interacts with TAF1AProteinHetionet hetionet:interacts:7157-9015Inferred only
UBC interacts with TAF1AProteinHetionet hetionet:interacts:7316-9015Inferred only
UBTF interacts with TAF1AProteinHetionet hetionet:interacts:7343-9015Inferred only
TAF1A participates in B-WICH complex positively regulates rRNA expressionPathwayReactome R-HSA-5250924Inferred only
TAF1A participates in Epigenetic regulation of gene expressionPathwayReactome R-HSA-212165Inferred only
TAF1A participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
TAF1A participates in Negative epigenetic regulation of rRNA expressionPathwayReactome R-HSA-5250941Inferred only
TAF1A participates in NoRC negatively regulates rRNA expressionPathwayReactome R-HSA-427413Inferred only
TAF1A participates in Positive epigenetic regulation of rRNA expressionPathwayReactome R-HSA-5250913Inferred only
TAF1A participates in RNA Polymerase I Promoter EscapePathwayReactome R-HSA-73772Inferred only
TAF1A participates in RNA Polymerase I TranscriptionPathwayReactome R-HSA-73864Inferred only
TAF1A participates in RNA Polymerase I Transcription InitiationPathwayReactome R-HSA-73762Inferred only
TAF1A participates in RNA Polymerase I Transcription TerminationPathwayReactome R-HSA-73863Inferred only
TAF1A participates in SIRT1 negatively regulates rRNA expressionPathwayReactome R-HSA-427359Inferred only
TAF1A participates in Transcription activation RNA polymerase I and KAT2A B and inhibition NuRD complex PathwayWikiPathways WP5565Inferred only
TAF1A regulates regulation of DNA-templated transcriptionBiological processgene ontology Q15573|GO:0006355Inferred only

Other names

7 names

Resolves to: TAF1A

Also called: RNA polymerase I-specific TBP-associated factor 48 kDaSL1TAFI48TATA box-binding protein-associated factor 1ATBP-associated factor 1ATranscription factor SL1Transcription initiation factor SL1/TIF-IB subunit A

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