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Proteins/UNIPROT:Q8WYL5
Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein..
Function from UniProtKB (Q8WYL5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
16 statements
16 statements · 3 reference databases · Subject: SSH1 · Sources: gene ontology, Hetionet, WikiPathways
3 reactions
5 names
Resolves to: SSH1
O-phospho-L-seryl-[protein]+waterL-seryl-[protein]+hydrogenphosphate
Catalysed by PPP6C or CTDSP2 or PPEF1 or PPEF2 or CTDSPL or PPM1D or PPM1G or PHLPP1 or CDC14B or PPM1B or DUSP14 or EPM2A and 61 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:20629CC BY 4.0Reference data
O-phospho-L-threonyl-[protein]+waterL-threonyl-[protein]+hydrogenphosphate
Catalysed by PPP6C or CTDSP2 or PPEF1 or PPEF2 or CTDSPL or PPM1D or PPM1G or PHLPP1 or CDC14B or PPM1B or DUSP14 or EPM2A and 59 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47004CC BY 4.0Reference data