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Proteins/UNIPROT:Q8IYR2
Protein-lysine N-methyltransferase. Monomethylates PRMT5, modulating its transcriptional activity. May also act as a histone methyltransferase (By similarity). Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1 (By similarity)..
Function from UniProtKB (Q8IYR2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
5 statements
5 statements · 2 reference databases · Subject: SMYD4 · Sources: Hetionet, WikiPathways
1 reaction
2 names
Resolves to: SMYD4
Rhea RHEA:51736CC BY 4.0Reference data