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Proteins/UNIPROT:P48764
Plasma membrane Na(+)/H(+) antiporter. Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis (By similarity). Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation..
Function from UniProtKB (P48764), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · transported by
1 compound
1 compound.
0 reported routes1 assembled route
3 rows
36 statements
36 statements · 6 reference databases · Subject: SLC9A3 · Sources: gene ontology, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
3 reactions
sodium(1+)+ammoniumsodium(1+)+ammonium
Transported by SLC9A3 or SLC9A1 or SLC9A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR01528CC BY 4.0Reference data
4 names
Resolves to: SLC9A3
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR05430CC BY 4.0Reference data
sodium(1+)+hydronsodium(1+)+hydron
Transported by SLC9A1 or SLC9A3 or SLC9A5 or SLC9A4 or SLC9B2 or SLC9A9 or SLC9A6 or SLC9A7 or SLC9A2 or SLC9A8
Reaction pageReversibleBalanced
Rhea RHEA:29419CC BY 4.0Reference data