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Proteins/UNIPROT:Q32P28
Has prolyl 3-hydroxylase activity and catalyzes the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in pro-collagen chains, a critical step for the formation of mature collagen trimers. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts..
Function from UniProtKB (Q32P28), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
41 statements
41 statements · 5 reference databases · Subject: P3H1 · Sources: gene ontology, Hetionet, Reactome, UniProt, WikiPathways
1 reaction
L-prolyl-[collagen]+2-oxoglutarate(2-)+dioxygentrans-3-hydroxy-L-prolyl-[collagen]+succinate(2-)+carbon dioxide
Catalysed by P3H1 or P3H2 or P3H3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:22872CC BY 4.0Reference data
5 names
Resolves to: P3H1