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Proteins/UNIPROT:Q96GJ1
Mitochondrial S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine in tRNAs and 12S rRNA. Catalyzes the methylation of uridine at position 54 (m5U54) in all tRNAs. Specifically methylates the uridine in position 429 of 12S rRNA (m5U429). Does not affect RNA stability or mitochondrial translation..
Function from UniProtKB (Q96GJ1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
31 statements
31 statements · 1 reference database · Subject: TRMT2B · Sources: Hetionet
2 reactions
CHEBI:65315+S-adenosyl-L-methionineCHEBI:74447+S-adenosyl-L-homocysteine+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:42712CC BY 4.0Reference data
a uridine in 12S rRNA+S-adenosyl-L-methioninea 5-methyluridine in 12S rRNA+S-adenosyl-L-homocysteine+hydron
Catalysed by TRMT2B
4 names
Resolves to: TRMT2B
Rhea RHEA:69859CC BY 4.0Reference data