myoclonus-dystonia syndrome
Findings
No curated finding names myoclonus-dystonia syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Myoclonus-dystonia syndrome (MDS) is a rare movement disorder characterized by mild to moderate dystonia along with 'lightning-like' myoclonic jerks.
Definition from the Mondo Disease Ontology (MONDO:0000903), read 2026-09-29. CC BY 4.0.
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- DystoniaHPOHP:0001332
- Very frequent (80% to 99% of cases)
- Limb myoclonusHPOHP:0045084
- Very frequent (80% to 99% of cases)
- MyoclonusHPOHP:0001336
- Very frequent (80% to 99% of cases)
- Spinal myoclonusHPOHP:0010531
- Very frequent (80% to 99% of cases)
- AnxietyHPOHP:0000739
- Frequent (30% to 79% of cases)
- Compulsive behaviorsHPOHP:0000722
- Frequent (30% to 79% of cases)
- DepressionHPOHP:0000716
- Frequent (30% to 79% of cases)
- Panic attackHPOHP:0025269
- Frequent (30% to 79% of cases)
- Personality disorderHPOHP:0012075
- Frequent (30% to 79% of cases)
- TorticollisHPOHP:0000473
- Frequent (30% to 79% of cases)
- Writer's crampHPOHP:0002356
- Frequent (30% to 79% of cases)
Genes
2 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
- A kind of
- Narrower terms (3)
Other names
4 names
Resolves to: myoclonus-dystonia syndrome
- Also called
- dystonia with myoclonusDYT-SGCEhereditary essential myoclonusmyoclonic dystonia