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Proteins/UNIPROT:P26006
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration..
(Microbial infection) Integrin ITGA3:ITGB1 may act as a receptor for R.delemar CotH7 in alveolar epithelial cells, which may be an early step in pulmonary mucormycosis disease progression..
Function from UniProtKB (P26006), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
104 statements
104 statements · 4 reference databases · Subject: ITGA3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
8 names
Resolves to: ITGA3