Proteins/UNIPROT:Q9UPZ3

HPS5

ProteinUNIPROT:Q9UPZ3

May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins..

Function from UniProtKB (Q9UPZ3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

Hermansky-Pudlak syndrome 5 has a germline basis in HPS5DiseaseGenCC HGNC:17022|MONDO:0013557Inferred only
Hermansky-Pudlak syndrome without pulmonary fibrosis has a germline basis in HPS5DiseaseGenCC HGNC:17022|MONDO:0016502Inferred only

Statements

19 statements

19 statements · 1 reference database · Subject: HPS5 · Sources: Hetionet

Order

CEP68 covaries with HPS5ProteinHetionet hetionet:covaries:11234-23177Inferred only
HPS5 covaries with FCRL6ProteinHetionet hetionet:covaries:11234-343413Inferred only
HPS5 covaries with FRAT2ProteinHetionet hetionet:covaries:11234-23401Inferred only
MTERF1 covaries with HPS5ProteinHetionet hetionet:covaries:11234-7978Inferred only
PCDHB10 covaries with HPS5ProteinHetionet hetionet:covaries:11234-56126Inferred only
HPS5 covaries with SPOCD1ProteinHetionet hetionet:covaries:11234-90853Inferred only
TESK1 covaries with HPS5ProteinHetionet hetionet:covaries:11234-7016Inferred only
ZNF641 covaries with HPS5ProteinHetionet hetionet:covaries:11234-121274Inferred only
HPS5 interacts with HPS6ProteinHetionet hetionet:interacts:11234-79803Inferred only
ITGA3 interacts with HPS5ProteinHetionet hetionet:interacts:11234-3675Inferred only
UBC interacts with HPS5ProteinHetionet hetionet:interacts:11234-7316Inferred only
CTRB1 increases the expression of HPS5ProteinHetionet hetionet:regulates:1504-11234Inferred only

Show the remaining 7

DLD increases the expression of HPS5ProteinHetionet hetionet:regulates:1738-11234Inferred only
FHL2 decreases the expression of HPS5ProteinHetionet hetionet:regulates:2274-11234Inferred only
MSRA increases the expression of HPS5ProteinHetionet hetionet:regulates:4482-11234Inferred only
PTMS increases the expression of HPS5ProteinHetionet hetionet:regulates:5763-11234Inferred only
SGCB increases the expression of HPS5ProteinHetionet hetionet:regulates:6443-11234Inferred only
TM9SF3 increases the expression of HPS5ProteinHetionet hetionet:regulates:56889-11234Inferred only
XBP1 increases the expression of HPS5ProteinHetionet hetionet:regulates:7494-11234Inferred only

Other names

6 names

Resolves to: HPS5

Also called: AIBP63Alpha-integrin-binding protein 63Hermansky-Pudlak syndrome 5 proteinKIAA1017Ru2Ruby-eye protein 2 homolog

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