Proteins/UNIPROT:Q86YJ7

ANKRD13B

ProteinUNIPROT:Q86YJ7

Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane..

Function from UniProtKB (Q86YJ7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

6 statements

6 statements · 2 reference databases · Subject: ANKRD13B · Sources: gene ontology, Hetionet

Order

BTN2A1 covaries with ANKRD13BProteinHetionet hetionet:covaries:11120-124930Inferred only
HES6 covaries with ANKRD13BProteinHetionet hetionet:covaries:124930-55502Inferred only
RPLP1 interacts with ANKRD13BProteinHetionet hetionet:interacts:124930-6176Inferred only
UBC interacts with ANKRD13BProteinHetionet hetionet:interacts:124930-7316Inferred only
ANKRD13B regulates negative regulation of receptor internalizationBiological processgene ontology Q86YJ7|GO:0002091Inferred only
ANKRD13B regulates regulation of receptor-mediated endocytosisBiological processgene ontology Q86YJ7|GO:0048259Inferred only

Other names

1 name

Resolves to: ANKRD13B

Also called: Ankyrin repeat domain-containing protein 13B

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