Proteins/UNIPROT:Q7L1Q6

BZW1

ProteinUNIPROT:Q7L1Q6

Translation initiation regulator which represses repeat-associated non-AUG (RAN) initiated translation probably by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function. Enhances histone H4 gene transcription but does not seem to bind DNA directly..

Function from UniProtKB (Q7L1Q6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

18 statements

18 statements · 2 reference databases · Subject: BZW1 · Sources: gene ontology, Hetionet

Order

BZW1 covaries with C1QL3ProteinHetionet hetionet:covaries:389941-9689Inferred only
BZW1 covaries with HES6ProteinHetionet hetionet:covaries:55502-9689Inferred only
BZW1 covaries with KCTD12ProteinHetionet hetionet:covaries:115207-9689Inferred only
BZW1 covaries with RPL38ProteinHetionet hetionet:covaries:6169-9689Inferred only
BZW1 covaries with RPS16ProteinHetionet hetionet:covaries:6217-9689Inferred only
BZW1 covaries with SHISA7ProteinHetionet hetionet:covaries:729956-9689Inferred only
BZW1 covaries with SNF8ProteinHetionet hetionet:covaries:11267-9689Inferred only
CDK2 interacts with BZW1ProteinHetionet hetionet:interacts:1017-9689Inferred only
ESR1 interacts with BZW1ProteinHetionet hetionet:interacts:2099-9689Inferred only
UBC interacts with BZW1ProteinHetionet hetionet:interacts:7316-9689Inferred only
VAV2 interacts with BZW1ProteinHetionet hetionet:interacts:7410-9689Inferred only
BZW1 regulates regulation of translational initiationBiological processgene ontology Q7L1Q6|GO:0006446Inferred only

Show the remaining 6

ACO2 decreases the expression of BZW1ProteinHetionet hetionet:regulates:50-9689Inferred only
BRAF decreases the expression of BZW1ProteinHetionet hetionet:regulates:673-9689Inferred only
NEK7 decreases the expression of BZW1ProteinHetionet hetionet:regulates:140609-9689Inferred only
PRKACA decreases the expression of BZW1ProteinHetionet hetionet:regulates:5566-9689Inferred only
STK10 increases the expression of BZW1ProteinHetionet hetionet:regulates:6793-9689Inferred only
TARS1 decreases the expression of BZW1ProteinHetionet hetionet:regulates:6897-9689Inferred only

Other names

6 names

Resolves to: BZW1

Also called: 5MP2Basic leucine zipper and W2 domain-containing protein 1BZAP45KIAA0005OrfProtein Orf

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