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Proteins/UNIPROT:Q9UL51
Hyperpolarization-activated ion channel that is permeable to sodium and potassium ions. Displays lower selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron (By similarity). Involved in the initiation of neuropathic pain in sensory neurons (By similarity)..
Function from UniProtKB (Q9UL51), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 2 · transported by
2 compounds
2 compounds.
0 reported routes2 assembled routes
2 rows
18 statements
18 statements · 6 reference databases · Subject: HCN2 · Sources: Bgee, gene ontology, Hetionet, Reactome, Rhea, WikiPathways
3 reactions
3 names
Resolves to: HCN2
Transported by ANO9 or HTR3E or KCNU1 or KCNJ18 or TMEM150C or KCNK1 or KCNK3 or GRIN2D or KCNN4 or KCNQ3 or KCNQ2 or HCN1 and 136 more alternatives
Reaction pageDirection not assertedBalanced
Rhea RHEA:29463CC BY 4.0Reference data
Transported by ANO9 or HTR3E or TMEM150C or KCNK1 or KCNK3 or GRIN2D or GRID2 or KCNQ3 or KCNQ2 or GRIN3B or HCN1 or TRPA1 and 98 more alternatives
Reaction pageRight to leftBalanced
Rhea RHEA:34963CC BY 4.0Reference data