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Proteins/UNIPROT:P12081
Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). Plays a role in axon guidance..
Function from UniProtKB (P12081), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
75 statements
75 statements · 6 reference databases · Subject: HARS1 · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
2 reactions
ATP+CHEBI:15971+MAM03071cAMP+MAM02380c+diphosphate(3-)
Catalysed by HARS1
Reaction pageLeft to rightBalance undeterminableEC 6.1.1.21cytosol
Human-GEM MAR05139CC BY 4.0Reference data
CHEBI:78442+L-histidine+ATP(4-)CHEBI:78527+AMP+diphosphate(3-)+
4 names
Resolves to: HARS1
Reaction pageDirection not assertedBalanced
Rhea RHEA:17313CC BY 4.0Reference data