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Proteins/UNIPROT:Q8IV16
Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (By similarity). Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries (By similarity). Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain APOA5. Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL (By similarity)..
Function from UniProtKB (Q8IV16), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
23 statements
23 statements · 4 reference databases · Subject: GPIHBP1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
2 reactions
MAM01570eMAM01569e+77243a triacylglycerol
Catalysed by MGLL or ABHD12 or SDC1 or ABHD6 or LPL or GPIHBP1
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.34, 3.1.1.23extracellular space
Human-GEM MAR00001CC BY 4.0Reference data
MAM03147e10385a triacylglycerol+MAM03146e
4 names
Resolves to: GPIHBP1
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.34, 3.1.1.23extracellular space
Human-GEM MAR00006CC BY 4.0Reference data