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Proteins/UNIPROT:Q6B8I1
Probable protein tyrosine phosphatase. Has phosphatase activity with synthetic substrates. Has a phosphatase activity-independent regulatory role in MAP3K5/ASK1-mediated apoptosis, preventing MAP3K5/ASK1 inhibition by AKT1. Shows no phosphatase activity on MAPK1/ERK2, MAPK8/JNK, MAPK14/p38 and MAP3K5/ASK1..
Function from UniProtKB (Q6B8I1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 statement
1 statement · 1 reference database · Subject: DUSP13A · Sources: Hetionet
3 reactions
5 names
Resolves to: DUSP13A
O-phospho-L-seryl-[protein]+waterL-seryl-[protein]+hydrogenphosphate
Catalysed by PPP6C or CTDSP2 or PPEF1 or PPEF2 or CTDSPL or PPM1D or PPM1G or PHLPP1 or CDC14B or PPM1B or DUSP14 or EPM2A and 61 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:20629CC BY 4.0Reference data
O-phospho-L-threonyl-[protein]+waterL-threonyl-[protein]+hydrogenphosphate
Catalysed by PPP6C or CTDSP2 or PPEF1 or PPEF2 or CTDSPL or PPM1D or PPM1G or PHLPP1 or CDC14B or PPM1B or DUSP14 or EPM2A and 59 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47004CC BY 4.0Reference data