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Proteins/UNIPROT:Q9Y5B0
Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation..
Function from UniProtKB (Q9Y5B0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
56 statements
56 statements · 4 reference databases · Subject: CTDP1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
2 reactions
2 names
Resolves to: CTDP1
O-phospho-L-threonyl-[protein]+waterL-threonyl-[protein]+hydrogenphosphate
Catalysed by PPP6C or CTDSP2 or PPEF1 or PPEF2 or CTDSPL or PPM1D or PPM1G or PHLPP1 or CDC14B or PPM1B or DUSP14 or EPM2A and 59 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47004CC BY 4.0Reference data