Proteins/UNIPROT:Q9NPH0

ACP6

ProteinUNIPROT:Q9NPH0Lysophosphatidic acid phosphatase type 6

Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid..

Function from UniProtKB (Q9NPH0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

17 statements

17 statements · 4 reference databases · Subject: ACP6 · Sources: Hetionet, Reactome, Rhea, WikiPathways

Order

ZNF550 covaries with ACP6ProteinHetionet hetionet:covaries:162972-51205Inferred only
GNG7 interacts with ACP6ProteinHetionet hetionet:interacts:2788-51205Inferred only
ACP6 interacts with SLC35F6ProteinHetionet hetionet:interacts:51205-54978Inferred only
ACP6 participates in 1q21 1 copy number variation syndromePathwayWikiPathways WP4905Inferred only
ACP6 participates in Glycerophospholipid biosynthesisPathwayReactome R-HSA-1483206Inferred only
ACP6 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
ACP6 participates in Metabolism of lipidsPathwayReactome R-HSA-556833Inferred only
ACP6 participates in Phospholipid metabolismPathwayReactome R-HSA-1483257Inferred only
ACP6 participates in Synthesis of PAPathwayReactome R-HSA-1483166Inferred only
ATP11B decreases the expression of ACP6ProteinHetionet hetionet:regulates:23200-51205Inferred only
AXL decreases the expression of ACP6ProteinHetionet hetionet:regulates:558-51205Inferred only
HDAC4 decreases the expression of ACP6ProteinHetionet hetionet:regulates:9759-51205Inferred only

Show the remaining 5

HEY2 decreases the expression of ACP6ProteinHetionet hetionet:regulates:23493-51205Inferred only
PLPP1 decreases the expression of ACP6ProteinHetionet hetionet:regulates:8611-51205Inferred only
TSHZ3 decreases the expression of ACP6ProteinHetionet hetionet:regulates:57616-51205Inferred only
1-(9Z-octadecenoyl)-sn-glycero-3-phosphate is a substrate of ACP6CompoundRhea RHEA:39835Inferred only
a 1-acyl-sn-glycero-3-phosphate is a substrate of ACP6CompoundRhea RHEA:33155Inferred only

Reactions

3 reactions

MAM01020e+waterphosphate(3-)+4-nitrophenol
Catalysed by ACP3 or ACP5 or ACP2 or ACP4 or PXYLP1 or ALPL or ACP6 or ALPP or ALPG or ALPI
Reaction pageLeft to rightBalancedEC 3.1.3.1, 3.1.3.2, 3.1.3.41extracellular space
Human-GEM MAR09569CC BY 4.0Reference data

Other names

5 names

Resolves to: ACP6

Also called: Acid phosphatase 6, lysophosphatidicAcid phosphatase-like protein 1ACPL1LPAPPACPL1

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