Pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter
The type 2 promoters can recruit TFIIIC without the help of TFIIIA because TFIIIC binds directly to the A and B boxes. As for the type 1 promoters, this then allows the binding of Brf1-TFIIIB and RNA polymerase III. Importantly, in the yeast system, once Brf1-TFIIIB has been recruited to type 1 or 2 promoters, TFIIIA and/or TFIIIC can be stripped from the DNA with high salt or heparin treatment. Brf1-TFIIIB remains bound to the DNA and is sufficient to direct multiple rounds of transcription.
REACT:R-HSA-76066Reactome
What the reference databases state
Statements
26 statements
26 statements · 1 reference database · Subject: RNA Polymerase III Transcription Initiation From Type 2 Promoter · Sources: Reactome
- BDP1 participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- BRF1 participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- CRCP participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- GTF3C1 participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- GTF3C2 participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- GTF3C3 participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- GTF3C4 participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- GTF3C5 participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- GTF3C6 participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR1C participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR2E participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR2F participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
Show the remaining 14
- POLR2H participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR2K participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR2L participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR3A participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR3B participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR3C participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR3D participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR3E participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR3F participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR3G participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR3GL participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR3H participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- POLR3K participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only
- TBP participates in RNA Polymerase III Transcription Initiation From Type 2 PromoterProteinReactome R-HSA-76066Inferred only