Pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter
The type 1 promoters recruit TFIIIA, the founding member of the C2H2 zinc finger family of DNA-binding proteins. The binding of TFIIIA then allows the binding of TFIIC, a complex consisting of five subunits (which differs from the six subunits in S. cerevisiae) in human cells and S. pombe. Once the DNA/TFIIIA/TFIIIC complex is formed, Brf1-TFIIIB joins the complex and this in turn allows the recruitment of RNA polymerase III.
REACT:R-HSA-76061Reactome
What the reference databases state
Statements
27 statements
27 statements · 1 reference database · Subject: RNA Polymerase III Transcription Initiation From Type 1 Promoter · Sources: Reactome
- BDP1 participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- BRF1 participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- CRCP participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- GTF3A participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- GTF3C1 participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- GTF3C2 participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- GTF3C3 participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- GTF3C4 participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- GTF3C5 participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- GTF3C6 participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR1C participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR2E participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
Show the remaining 15
- POLR2F participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR2H participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR2K participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR2L participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR3A participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR3B participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR3C participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR3D participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR3E participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR3F participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR3G participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR3GL participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR3H participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- POLR3K participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only
- TBP participates in RNA Polymerase III Transcription Initiation From Type 1 PromoterProteinReactome R-HSA-76061Inferred only