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(9Z-octadecenoyl)-glycerol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

171 compounds within 3 steps: 2 in 1, 20 in 2, 149 in 3

Does it reach a compound?

Three steps

1,3-di-(9Z-octadecenoyl)-glycerolReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,3-di-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by PNLIPRP2, SLC27A2, ACSL3, ACSL1 and 7 moreOne of 2 routes
2,3-di-(9Z)-octadecenoyl-sn-glycerolReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
3. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)
Catalysed by PNLIPRP2, DGAT1, LIPA, PNPLA4 and 3 moreOne of 2 routes
1-(9Z-octadecenoyl)-3-hexadecanoylglycerolReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-hexadecanoylglycerol + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-3-hexadecanoylglycerol + CoA
Catalysed by PNLIPRP2, SLC27A2, ACSL3, ACSL1 and 7 more
di-(9Z)-octadecenoylglycerolReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
3. 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = di-(9Z)-octadecenoylglycerol + (9Z)-octadecenoate + H(+)
Catalysed by PNLIPRP2, DGAT1, LIPA, PNPLA4 and 9 moreOne of 2 routes
1-O-hexadecyl-3-(9Z)-octadecenoylglycerolReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-O-hexadecylglycerol + (9Z)-octadecenoyl-CoA = 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol + CoA
Catalysed by PNLIPRP2, SLC27A2, ACSL3, ACSL1 and 6 more
1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by PNLIPRP2, ABHD12, LPGAT1
O-dodecanoyl-R-carnitineReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. Utilized Transport
3. carnitine O-palmitoyltransferase (dodecanoylcarnitine)
Catalysed by PNLIPRP2, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosolOne of 7 routes
(11Z,14Z)-eicosadienoateReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PNLIPRP2cytosol, extracellular spaceOne of 12 routes
(17Z)-hexacosenoateReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PNLIPRP2cytosol, extracellular spaceOne of 12 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoateReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PNLIPRP2cytosol, extracellular spaceOne of 12 routes
(7Z,10Z,13Z,16Z)-docosatetraenoateReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PNLIPRP2cytosol, extracellular spaceOne of 12 routes
1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by PNLIPRP2, SLC27A2, ACSL3, ACSL1 and 8 more
1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by PNLIPRP2, SLC27A2, ACSL3, ACSL1 and 6 more
(2E,9Z)-octadecadienoyl-CoAReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. long-chain-fatty-acid-CoA ligase (oleate)
3. medium-chain acyl-CoA dehydrogenase (oleoyl-CoA)
Catalysed by PNLIPRP2, SLC27A2, ACSL4, ACSL3 and 9 morecytosol, mitochondrial matrixOne of 4 routes
(5Z,8Z,11Z)-eicosatrienoateReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PNLIPRP2cytosol, extracellular spaceOne of 12 routes
1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositolReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositol + CoA
Catalysed by PNLIPRP2, ABHD12, AGPAT3, AGPAT5
tricosanoateReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by PNLIPRP2cytosol, extracellular spaceOne of 12 routes
1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerolReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z)-octadecenoyl-CoA = 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by PNLIPRP2, SLC27A2, ACSL3, ACSL1 and 6 more
O-(9Z)-octadecenoyl-(R)-carnitineReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. (R)-carnitine + (9Z)-octadecenoyl-CoA = O-(9Z)-octadecenoyl-(R)-carnitine + CoA
Catalysed by PNLIPRP2, SLC27A2, ACSL3, ACSL1 and 6 more
O-4,8-dimethylnonanoyl-(R)-carnitineReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. Utilized Transport
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by PNLIPRP2, CRAT, CROTendoplasmic reticulum, cytosol, peroxisomeOne of 5 routes
1-decanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. (9Z-octadecenoyl)-glycerol + H2O = glycerol + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
3. 1-decanoylglycerol + (9Z)-octadecenoyl-CoA = 1-decanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by PNLIPRP2, SLC27A2, ACSL3, ACSL1 and 6 more

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