spermidine

Three steps

• cholesteryl (11Z)-octadecenoateReach from here →
  1. diamine N-acetyltransferase (N1-acetylspermidine)
  2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
  3. (11Z)-octadecenoyl-CoA + cholesterol = cholesteryl (11Z)-octadecenoate + CoA

  Catalysed by SAT1, SAT2, CPT1A, CPT1C and 2 morecytosol

• a 3-oxoacyl-CoAReach from here →
  1. diamine N-acetyltransferase (N1-acetylspermidine)
  2. acyl-CoA:sphingosine N-acyltransferase
  3. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA

  Catalysed by SAT1, SAT2, ASAH1, ACER2 and 6 morecytosol, Golgi apparatus

• taurochenodeoxycholateReach from here →
  1. diamine N-acetyltransferase (N1-acetylspermidine)
  2. Propanoyl-CoA:acetyl-CoA C-acyltransferase
  3. 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:taurine N-choloyltransferase

  Catalysed by SAT1, SAT2, ACAA1, SCP2 and 2 morecytosol, peroxisomeOne of 5 routes