Proteins/UNIPROT:O76041

NEBL

ProteinUNIPROT:O76041

Binds to actin and plays an important role in the assembly of the Z-disk. May functionally link sarcomeric actin to the desmin intermediate filaments in the heart muscle sarcomeres..

[Isoform 2]: May play a role in the assembly of focal adhesions..

Function from UniProtKB (O76041), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

dilated cardiomyopathy has a germline basis in NEBLDiseaseGenCC HGNC:16932|MONDO:0005021Inferred only
hypertrophic cardiomyopathy has a germline basis in NEBLDiseaseGenCC HGNC:16932|MONDO:0005045Inferred only

Statements

9 statements

9 statements · 1 reference database · Subject: NEBL · Sources: Hetionet

Order

H2AC7 covaries with NEBLProteinHetionet hetionet:covaries:10529-3013Inferred only
ACTB interacts with NEBLProteinHetionet hetionet:interacts:10529-60Inferred only
ACTN1 interacts with NEBLProteinHetionet hetionet:interacts:10529-87Inferred only
NEBL interacts with MED28ProteinHetionet hetionet:interacts:10529-80306Inferred only
NEBL interacts with MYPNProteinHetionet hetionet:interacts:10529-84665Inferred only
NEBL interacts with SMURF2ProteinHetionet hetionet:interacts:10529-64750Inferred only
NEBL interacts with TRIM63ProteinHetionet hetionet:interacts:10529-84676Inferred only
ZYX interacts with NEBLProteinHetionet hetionet:interacts:10529-7791Inferred only
STAT5B increases the expression of NEBLProteinHetionet hetionet:regulates:6777-10529Inferred only

Other names

4 names

Resolves to: NEBL

Also called: Actin-binding Z-disk proteinC10orf113LNEBLNebulette

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