Compound
nitrite
Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Structure
Loading the model…
- Class
- Inorganic compound, anion
- Formula
- NO2
- Mass
- 46.005 g/mol
- Charge
- -1
- InChIKey
- IOVCWXUNBOPUCH-UHFFFAOYSA-M
- SMILES
- O=N[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
10 entities
10 entities reached.
0 reported hops10 assembled from the scaffold
- nitrateCompoundCHEBI:17632converted toInferred only66 paths17 endpoints
- MPOProteinUNIPROT:P05164substrate ofInferred only26 paths13 endpoints
- PRDX6ProteinUNIPROT:P30041substrate ofInferred only15 paths15 endpoints
- PXDNProteinUNIPROT:Q92626substrate ofInferred only14 paths14 endpoints
- SUOXProteinUNIPROT:P51687substrate ofInferred only11 paths11 endpoints
- LPOProteinUNIPROT:P22079substrate ofInferred only10 paths5 endpoints
- CYGBProteinUNIPROT:Q8WWM9substrate ofInferred only5 paths5 endpoints
- MBProteinUNIPROT:P02144substrate ofInferred only4 paths4 endpoints
- EPXProteinUNIPROT:P11678substrate ofInferred only3 paths3 endpoints
- NGBProteinUNIPROT:Q9NPG2substrate ofInferred only2 paths2 endpoints
What the reference databases state
Statements
16 statements
16 statements · 2 reference databases · Subject: nitrite · Sources: Human-GEM, Rhea
- nitrite is converted to nitrateCompoundRhea RHEA:19061Inferred only
- nitrite is converted to nitrateCompoundRhea RHEA:17913Inferred only
- nitrate is converted to nitriteCompoundRhea RHEA:17913Inferred only
- nitrate is converted to nitriteCompoundRhea RHEA:19061Inferred only
- nitric oxide is converted to nitriteCompoundRhea RHEA:78539Inferred only
- nitrite is a substrate of CYGBProteinRhea RHEA:77711Inferred only
- nitrite is a substrate of EPXProteinHuman-GEM MAR06536Inferred only
- nitrite is a substrate of LPOProteinHuman-GEM MAR03147Inferred only
- nitrite is a substrate of LPOProteinHuman-GEM MAR06536Inferred only
- nitrite is a substrate of MBProteinRhea RHEA:77711Inferred only
- nitrite is a substrate of MPOProteinHuman-GEM MAR03152Inferred only
- nitrite is a substrate of MPOProteinHuman-GEM MAR03148Inferred only
Show the remaining 4
- nitrite is a substrate of NGBProteinRhea RHEA:77711Inferred only
- nitrite is a substrate of PRDX6ProteinHuman-GEM MAR03148Inferred only
- nitrite is a substrate of PXDNProteinHuman-GEM MAR06536Inferred only
- nitrite is a substrate of SUOXProteinRhea RHEA:57488Inferred only
Reactions
90 reactions
proton+hypochlorous acid+nitritewater+MAM02591e
Catalysed by LPO
Reaction pageReversibleBalancedEC 1.11.1.7extracellular space
Human-GEM MAR03147CC BY 4.0Reference data
proton+hypochlorous acid+nitritewater+MAM02591l
Reaction pageReversibleBalancedEC 1.11.1.7lysosome
Human-GEM MAR03148CC BY 4.0Reference data
proton+hypochlorous acid+nitritewater+MAM02591n
Catalysed by MPO
Reaction pageReversibleBalancedEC 1.11.1.7nucleus
Human-GEM MAR03152CC BY 4.0Reference data
MAM01117cMAM01936c+nitrite
Reaction pageReversibleUnbalancedcytosol
Human-GEM MAR06459CC BY 4.0Reference data
proton+hypochlorous acid+nitritewater+MAM02591c
Catalysed by EPX or PXDN or LPO
Reaction pageReversibleBalancedEC 1.11.1.7cytosol
Human-GEM MAR06536CC BY 4.0Reference data
MAM00991c+2protonMAM01003c+nitrite
Reaction pageReversibleUnbalancedcytosol
Human-GEM MAR06792CC BY 4.0Reference data
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06991CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09149CC BY 4.0Reference data
Reaction pageReversibleBalancedextracellular space, cytosol
Human-GEM MAR12088CC BY 4.0Reference data
2Fe(II)-[cytochrome]+nitrate+2hydron2Fe(III)-[cytochrome]+nitrite+water
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:12909CC BY 4.0Reference data
6Fe(III)-[cytochrome c]+ammonium+2water6Fe(II)-[cytochrome c]+nitrite+8hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13089CC BY 4.0Reference data
nitric oxide+Fe(III)-[cytochrome c]+waterFe(II)-[cytochrome c]+nitrite+2hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:15233CC BY 4.0Reference data
Other names
17 names
Resolves to: nitrite
- Also called
- [NO2](-)[NO2]−Nitritnitrite anionNITRITE IONnitrite(1-)nitrite(1−)nitrous acid, ion(1-)nitrous acid, ion(1−)NO2NO2(-)NO2−
- Systematic name
- dioxidonitrate(1-)dioxidonitrate(1−)dioxonitrate(1-)dioxonitrate(1−)dioxonitrate(III)