What the reference databases state
Statements
7 statements
7 statements · 1 reference database · Subject: 7alpha-hydroxycholest-4-en-3-one · Sources: Human-GEM
- 25-hydroxycholesterol is converted to 7alpha-hydroxycholest-4-en-3-oneCompoundHuman-GEM MAR02184Inferred only
- 7alpha-hydroxycholest-4-en-3-one is converted to 25-hydroxycholesterolCompoundHuman-GEM MAR02184Inferred only
- 7alpha-hydroxycholesterol is converted to 7alpha-hydroxycholest-4-en-3-oneCompoundHuman-GEM MAR02860Inferred only
- 7alpha-hydroxycholesterol is converted to 7alpha-hydroxycholest-4-en-3-oneCompoundHuman-GEM MAR01584Inferred only
- 7alpha-hydroxycholest-4-en-3-one is converted to 7alpha-hydroxycholesterolCompoundHuman-GEM MAR02860Inferred only
- 7alpha-hydroxycholesterol is converted to 7alpha-hydroxycholest-4-en-3-oneCompoundHuman-GEM MAR01585Inferred only
- 7alpha-hydroxycholest-4-en-3-one is a substrate of HSD3B7ProteinHuman-GEM MAR02184Inferred only
Reactions
20 reactions
7alpha-hydroxycholesterol+NAD(+)7alpha-hydroxycholest-4-en-3-one+proton+NADH(2-)
Catalysed by HSD3B7
Reaction pageLeft to rightBalancedEC 1.1.1.181GO:0005783
Human-GEM MAR01584CC BY 4.0Reference data
7alpha-hydroxycholesterol+NADP(3-)7alpha-hydroxycholest-4-en-3-one+proton+NADPH(4-)
Catalysed by HSD3B7
Reaction pageLeft to rightBalancedEC 1.1.1.181GO:0005783
Human-GEM MAR01585CC BY 4.0Reference data
7alpha-hydroxycholest-4-en-3-one+proton+NADPH(4-)+dioxygenMAM01178r+water+NADP(3-)
Catalysed by CYP8B1
Reaction pageLeft to rightBalancedEC 1.14.14.139GO:0005783
Human-GEM MAR01589CC BY 4.0Reference data
7alpha-hydroxycholest-4-en-3-one+proton+NADH(2-)+dioxygenMAM01178r+water+NAD(+)
Catalysed by CYP8B1
Reaction pageLeft to rightBalancedEC 1.14.14.139GO:0005783
Human-GEM MAR01590CC BY 4.0Reference data
7alpha-hydroxycholest-4-en-3-one7alpha-hydroxycholest-4-en-3-one
Reaction pageReversibleBalancedGO:0005829, GO:0005783
Human-GEM MAR01672CC BY 4.0Reference data
7alpha-hydroxycholest-4-en-3-one+proton+NADPH(4-)MAM01181c+NADP(3-)
Catalysed by AKR1D1
Reaction pageLeft to rightBalancedEC 1.3.1.3, 1.3.99.6GO:0005829
Human-GEM MAR01673CC BY 4.0Reference data
MAM00592r+NAD(+)7alpha-hydroxycholest-4-en-3-one+proton+NADH(2-)
Reaction pageLeft to rightBalancedEC 1.1.1.145, 5.3.3.1GO:0005783
Human-GEM MAR01783CC BY 4.0Reference data
MAM00623r+NAD(+)7alpha-hydroxycholest-4-en-3-one+proton+NADH(2-)
Reaction pageLeft to rightBalancedGO:0005783
Human-GEM MAR01787CC BY 4.0Reference data
25-hydroxycholesterol+NADP(3-)7alpha-hydroxycholest-4-en-3-one+proton+NADPH(4-)
Catalysed by HSD3B7
Reaction pageReversibleBalancedEC 1.1.1.181GO:0005783
Human-GEM MAR02184CC BY 4.0Reference data
7alpha-hydroxycholest-4-en-3-one+ATP+water7alpha-hydroxycholest-4-en-3-one+ADP+proton+phosphate(3-)
Reaction pageLeft to rightBalancedGO:0005783, GO:0005829
Human-GEM MAR02297CC BY 4.0Reference data
7alpha-hydroxycholesterol+NAD(+)7alpha-hydroxycholest-4-en-3-one+proton+NADH(2-)
Reaction pageReversibleBalancedEC 5.3.3.1GO:0005829
Human-GEM MAR02860CC BY 4.0Reference data
MAM00592m+NAD(+)7alpha-hydroxycholest-4-en-3-one+proton+NADH(2-)
Reaction pageReversibleBalancedEC 5.3.3.1GO:0005759
Human-GEM MAR02881CC BY 4.0Reference data