Loading the page.
Proteins/UNIPROT:Q99259
Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor..
[Isoform 3]: Enzymatically inactive as glutamate decarboxylase..
Function from UniProtKB (Q99259), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
50 statements
50 statements · 7 reference databases · Subject: GAD1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, UniProt, WikiPathways
3 reactions
3-sulfino-L-alanine+2protoncarbon dioxide+CHEBI:16668
Reaction pageLeft to rightBalancedEC 4.1.1.15, 4.1.1.29cytosol
Human-GEM MAR03910CC BY 4.0Reference data
5 names
Resolves to: GAD1
Human-GEM MAR04690CC BY 4.0Reference data
L-glutamate(1-)+hydron4-aminobutanoate+carbon dioxide
Reaction pageLeft to rightBalanced
Rhea RHEA:17785CC BY 4.0Reference data