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Papers/PMID:39354480

Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial.

Nutrition journal2024The record

6 findings · 1 compound · 6 endpoints · 3 null

What it reported

How to read these marks

What moved

3 findings

  • curcumin — decreases body mass index

    Evidence strength: moderate.Findingreplicated ×7
    “The means of body weight and body mass index were significantly lower in the curcumin-treated group compared to the placebo group at visits at 3, 6, 9, and 12 months (Table 2).”
    Quoted verbatim from Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial..
    Study
    RCT
    Dose
    curcuminoid extract 250 mg per capsule, three capsules twice daily (1500 mg curcuminoids a day) for 12 months
    Population
    Thai adults with recent type 2 diabetes, BMI 23 or above, all on metformin; difference at 3, 6, 9 and 12 months

    Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial.2024PMID:3935448010.1186/s12937-024-01022-3Industry fundedPermalink

  • curcumin — decreases glycated haemoglobin (HbA1c)

    Evidence strength: moderate.Findingreplicated ×4
    “The means of diabetes-related blood chemistries used to assess diabetic progression, such as HbA1c, FPG, were significantly lower in the curcumin-treated group compared to the placebo group at visits at 3,6, 9, and 12 months (Table 2).”
    Quoted verbatim from Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial..
    Study
    RCT
    Dose
    curcuminoid extract 250 mg per capsule, three capsules twice daily (1500 mg curcuminoids a day) for 12 months
    Population
    Thai adults with recent type 2 diabetes, well controlled (HbA1c below 6.5%), BMI 23 or above, all on metformin; difference at 3, 6, 9 and 12 months (Table 2 shows p less than 0.05 at 12 months)

    Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial.2024PMID:3935448010.1186/s12937-024-01022-3Industry fundedPermalink

  • curcumin — increases serum adiponectin

    Evidence strength: moderate.Findingreplicated ×3
    “The level of adiponectin in the placebo-treated group increased, while those of the curcumin-treated group increased significantly and became significantly different from that of the placebo-treated group at the 6-,9- and 12-month visits.”
    Quoted verbatim from Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial..
    Study
    RCT
    Dose
    curcuminoid extract 250 mg per capsule, three capsules twice daily (1500 mg curcuminoids a day) for 12 months
    Population
    Thai adults with recent type 2 diabetes, BMI 23 or above, all on metformin; difference at 6, 9 and 12 months

    Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial.2024PMID:3935448010.1186/s12937-024-01022-3Industry fundedPermalink

What did not

3 findings