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Catalyst

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

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A reference for what the literature reports. Not medical advice.

Reaction

15(S)-HPETEMAM00390c

Reversible · Balanced · EC 1.14.14.1

Compartment: cytosol

Inferred

Reference data, not a finding. Evidence key

Catalysts

CYP3A43
CYP2D6
CYP3A5
CYP2C18
CYP2E1
CYP2J2
CYP1B1
CYP2C9
CYP2C8
CYP1A1
CYP1A2
CYP4B1
CYP2U1
CYP3A4
CYP3A7
CYP2C19
CYP2S1
CYP4F11
CYP4Z1
CYP4F12
CYP4F8
CYP2B6
CYP2F1
CYP2A13
CYP2A7
CYP2A6

Human-GEM MAR00991·2.0.1·CC BY 4.0Reference data

15(S)-HPETE⇌MAM00390c

Catalysts

15(S)-HPETEMAM00390c