Proteins/UNIPROT:Q96PF2

TSSK2

ProteinUNIPROT:Q96PF2

Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body..

Function from UniProtKB (Q96PF2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

33 statements

33 statements · 3 reference databases · Subject: TSSK2 · Sources: Hetionet, UniProt, WikiPathways

Order

TSSK2 covaries with C1orf94ProteinHetionet hetionet:covaries:23617-84970Inferred only
TSSK2 covaries with CDCP2ProteinHetionet hetionet:covaries:200008-23617Inferred only
OBSCN covaries with TSSK2ProteinHetionet hetionet:covaries:23617-84033Inferred only
ZDHHC23 covaries with TSSK2ProteinHetionet hetionet:covaries:23617-254887Inferred only
APP interacts with TSSK2ProteinHetionet hetionet:interacts:23617-351Inferred only
HSP90AA1 interacts with TSSK2ProteinHetionet hetionet:interacts:23617-3320Inferred only
HSP90AB1 interacts with TSSK2ProteinHetionet hetionet:interacts:23617-3326Inferred only
SKIC2 interacts with TSSK2ProteinHetionet hetionet:interacts:23617-6499Inferred only
TFG interacts with TSSK2ProteinHetionet hetionet:interacts:10342-23617Inferred only
TSSK2 interacts with TSKSProteinHetionet hetionet:interacts:23617-60385Inferred only
TSSK2 participates in 22q11 2 copy number variation syndromePathwayWikiPathways WP4657Inferred only
TSSK2 decreases the expression of CDKN1BProteinHetionet hetionet:regulates:23617-1027Inferred only

Show the remaining 21

TSSK2 increases the expression of EIF4G1ProteinHetionet hetionet:regulates:23617-1981Inferred only
TSSK2 increases the expression of ERBB3ProteinHetionet hetionet:regulates:23617-2065Inferred only
TSSK2 decreases the expression of GNPDA1ProteinHetionet hetionet:regulates:23617-10007Inferred only
TSSK2 increases the expression of GPER1ProteinHetionet hetionet:regulates:23617-2852Inferred only
TSSK2 increases the expression of HACD3ProteinHetionet hetionet:regulates:23617-51495Inferred only
TSSK2 decreases the expression of HMG20BProteinHetionet hetionet:regulates:23617-10362Inferred only
TSSK2 decreases the expression of HSPB1ProteinHetionet hetionet:regulates:23617-3315Inferred only
TSSK2 increases the expression of MAN2B1ProteinHetionet hetionet:regulates:23617-4125Inferred only
TSSK2 increases the expression of MAP7ProteinHetionet hetionet:regulates:23617-9053Inferred only
TSSK2 increases the expression of MCOLN1ProteinHetionet hetionet:regulates:23617-57192Inferred only
TSSK2 increases the expression of ME2ProteinHetionet hetionet:regulates:23617-4200Inferred only
TSSK2 increases the expression of NFKBIAProteinHetionet hetionet:regulates:23617-4792Inferred only
TSSK2 decreases the expression of NPRL2ProteinHetionet hetionet:regulates:23617-10641Inferred only
TSSK2 decreases the expression of PIN1ProteinHetionet hetionet:regulates:23617-5300Inferred only
TSSK2 decreases the expression of S100A13ProteinHetionet hetionet:regulates:23617-6284Inferred only
TSSK2 decreases the expression of SLC35B1ProteinHetionet hetionet:regulates:23617-10237Inferred only
TSSK2 increases the expression of ST3GAL5ProteinHetionet hetionet:regulates:23617-8869Inferred only
TSSK2 decreases the expression of TM9SF3ProteinHetionet hetionet:regulates:23617-56889Inferred only
TSSK2 decreases the expression of TMSB15AProteinHetionet hetionet:regulates:23617-11013Inferred only
TSSK2 increases the expression of VAT1ProteinHetionet hetionet:regulates:23617-10493Inferred only
TSSK2 requires the cofactor magnesium(2+)CompoundUniProt Q96PF2Inferred only

Reactions

2 reactions

L-seryl-[protein]+ATP(4-)O-phospho-L-seryl-[protein]+ADP(3-)+hydron
Catalysed by SGK1 or CDC7 or PLK4 or STK25 or CIT or RIOK3 or MAP2K7 or CHEK1 or BCKDK or IKBKB or CASK or AURKA and 347 more alternatives
Reaction pageLeft to right

Other names

11 names

Resolves to: TSSK2

Also called: 22BDGS-GDGSGDiGeorge syndrome protein GSerine/threonine-protein kinase 22BSPOGA2STK22BTestis-specific kinase 2TSK-2TSK2TSSK-2

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