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Proteins/UNIPROT:Q15631
DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots..
Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand..
Function from UniProtKB (Q15631), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
45 statements
45 statements · 2 reference databases · Subject: TSN · Sources: Hetionet, Reactome
2 names
Resolves to: TSN