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Proteins/UNIPROT:Q8IZ69
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine in tRNAs and some mRNAs. Mainly catalyzes the methylation of uridine at position 54 (m5U54) in cytosolic tRNAs. Also able to mediate the formation of 5-methyl-uridine in some mRNAs..
Function from UniProtKB (Q8IZ69), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
41 statements
41 statements · 3 reference databases · Subject: TRMT2A · Sources: Bgee, Hetionet, WikiPathways
2 reactions
CHEBI:65315+S-adenosyl-L-methionineCHEBI:74447+S-adenosyl-L-homocysteine+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:42712CC BY 4.0Reference data
a uridine in mRNA+S-adenosyl-L-methioninea 5-methyluridine in mRNA+S-adenosyl-L-homocysteine+hydron
Catalysed by TRMT2A
2 names
Resolves to: TRMT2A
Rhea RHEA:69863CC BY 4.0Reference data