Proteins/UNIPROT:Q92797

SYMPK

ProteinUNIPROT:Q92797

Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing. Specific component of the tight junction (TJ) plaque, but might not be an exclusively junctional component. May have a house-keeping rule. Is involved in pre-mRNA polyadenylation. Enhances SSU72 phosphatase activity..

Function from UniProtKB (Q92797), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

36 statements

36 statements · 3 reference databases · Subject: SYMPK · Sources: gene ontology, Hetionet, Reactome

Order

SYMPK covaries with DHX40ProteinHetionet hetionet:covaries:79665-8189Inferred only
PPP1R3F covaries with SYMPKProteinHetionet hetionet:covaries:8189-89801Inferred only
SLF1 covaries with SYMPKProteinHetionet hetionet:covaries:8189-84250Inferred only
TEAD2 covaries with SYMPKProteinHetionet hetionet:covaries:8189-8463Inferred only
TMEM255A covaries with SYMPKProteinHetionet hetionet:covaries:55026-8189Inferred only
SYMPK covaries with TMEM59LProteinHetionet hetionet:covaries:25789-8189Inferred only
SYMPK covaries with ZNF10ProteinHetionet hetionet:covaries:7556-8189Inferred only
SYMPK covaries with ZNF641ProteinHetionet hetionet:covaries:121274-8189Inferred only
CSTF2 interacts with SYMPKProteinHetionet hetionet:interacts:1478-8189Inferred only
HSF1 interacts with SYMPKProteinHetionet hetionet:interacts:3297-8189Inferred only
HTT interacts with SYMPKProteinHetionet hetionet:interacts:3064-8189Inferred only
SYMPK interacts with SIRT7ProteinHetionet hetionet:interacts:51547-8189Inferred only

Show the remaining 24

SYMPK interacts with SSU72ProteinHetionet hetionet:interacts:29101-8189Inferred only
SUMO1 interacts with SYMPKProteinHetionet hetionet:interacts:7341-8189Inferred only
SUMO2 interacts with SYMPKProteinHetionet hetionet:interacts:6613-8189Inferred only
TOP1 interacts with SYMPKProteinHetionet hetionet:interacts:7150-8189Inferred only
UBC interacts with SYMPKProteinHetionet hetionet:interacts:7316-8189Inferred only
SYMPK participates in Dengue Virus InfectionPathwayReactome R-HSA-9839923Inferred only
SYMPK participates in Dengue Virus-Host InteractionsPathwayReactome R-HSA-9918481Inferred only
SYMPK participates in DiseasePathwayReactome R-HSA-1643685Inferred only
SYMPK participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
SYMPK participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
SYMPK participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only
SYMPK participates in mRNA 3'-end processingPathwayReactome R-HSA-72187Inferred only
SYMPK participates in mRNA PolyadenylationPathwayReactome R-HSA-9770562Inferred only
SYMPK participates in Processing of Capped Intron-Containing Pre-mRNAPathwayReactome R-HSA-72203Inferred only
SYMPK participates in Processing of Capped Intronless Pre-mRNAPathwayReactome R-HSA-75067Inferred only
SYMPK participates in Processing of Intronless Pre-mRNAsPathwayReactome R-HSA-77595Inferred only
SYMPK participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
SYMPK participates in RNA Polymerase II Transcription TerminationPathwayReactome R-HSA-73856Inferred only
SYMPK participates in Transport of Mature mRNA Derived from an Intronless TranscriptPathwayReactome R-HSA-159231Inferred only
SYMPK participates in Transport of Mature mRNAs Derived from Intronless TranscriptsPathwayReactome R-HSA-159234Inferred only
SYMPK participates in Transport of Mature Transcript to CytoplasmPathwayReactome R-HSA-72202Inferred only
SYMPK participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only
SYMPK regulates negative regulation of protein bindingBiological processgene ontology Q92797|GO:0032091Inferred only
PTPN1 increases the expression of SYMPKProteinHetionet hetionet:regulates:5770-8189Inferred only

Other names

2 names

Resolves to: SYMPK

Also called: SPKSymplekin

← Every protein Find it in the graph →