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Proteins/UNIPROT:Q96Q91
Electroneutral Cl(-)/HCO3(-) antiporter that favors chloride ion entry and efflux of hydrogencarbonate and sodium ion across the basolateral membrane and may participate in salivary secretion. Also mediates Cl(-)/HCO3(-) exchange activity in the presence of K(+) as well as Cs(+), Li(+), and Rb(+) (By similarity). Does not contribute to Cl(-)/HCO3(-) exchanger in the apical membrane of the upper villous epithelium (By similarity)..
Function from UniProtKB (Q96Q91), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
26 statements
26 statements · 4 reference databases · Subject: SLC4A9 · Sources: gene ontology, Human-GEM, Reactome, Rhea
8 reactions
chlorine(.)+hydrogencarbonatechlorine(.)+hydrogencarbonate
Transported by SLC4A1 or SLC26A4 or SLC26A3 or SLC4A9 or SLC4A3 or SLC4A2
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR06525CC BY 4.0Reference data
6 names
Resolves to: SLC4A9
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR08076CC BY 4.0Reference data
3hydrogencarbonate+sodium(1+)3hydrogencarbonate+sodium(1+)
Transported by SLC4A7 or SLC4A4 or SLC4A9 or SLC4A5
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR08077CC BY 4.0Reference data
2hydrogencarbonate+chloride+sodium(1+)2hydrogencarbonate+chloride+sodium(1+)
Transported by SLC4A8 or SLC4A10 or SLC4A9
Reaction pageDirection not assertedBalanced
Rhea RHEA:72739CC BY 4.0Reference data
K(+)+2hydrogencarbonate+chlorideK(+)+2hydrogencarbonate+chloride
Transported by SLC4A9
Reaction pageDirection not assertedBalanced
Rhea RHEA:75059CC BY 4.0Reference data
Li(+)+2hydrogencarbonate+chlorideLi(+)+2hydrogencarbonate+chloride
Transported by SLC4A9
Reaction pageDirection not assertedBalanced
Rhea RHEA:75063CC BY 4.0Reference data
Rb(+)+2hydrogencarbonate+chlorideRb(+)+2hydrogencarbonate+chloride
Transported by SLC4A9
Reaction pageDirection not assertedBalanced
Rhea RHEA:75067CC BY 4.0Reference data
Cs(+)+2hydrogencarbonate+chlorideCs(+)+2hydrogencarbonate+chloride
Transported by SLC4A9
Reaction pageDirection not assertedBalanced
Rhea RHEA:75071CC BY 4.0Reference data