Loading the page.
Proteins/UNIPROT:C9JLW8
The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition..
Function from UniProtKB (C9JLW8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
149 statements
149 statements · 3 reference databases · Subject: MCRIP1 · Sources: gene ontology, Hetionet, Reactome
4 names
Resolves to: MCRIP1