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Proteins/UNIPROT:Q96BZ9
GTPase-activating protein (GAP) specific for Rab1 and Rab2 small GTPase families for which it can accelerate the intrinsic GTP hydrolysis rate by more than five orders of magnitude. Also shows GAP activity for RAB18 GTPase. Promotes RAB18 dissociation from the endoplasmic reticulum (ER) membrane into the cytosol, probably through stimulating RAB18 GTP-hydrolysis. Involved in maintaining endoplasmic reticulum structure..
Function from UniProtKB (Q96BZ9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
104 statements
104 statements · 3 reference databases · Subject: TBC1D20 · Sources: gene ontology, Hetionet, Reactome
2 names
Resolves to: TBC1D20