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Proteins/UNIPROT:Q5JTW2
Centriole wall protein that localizes to mature centrioles and regulates centriole and cilia biogenesis. Involved in centrosome duplication: required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles. Involved in cilium biogenesis and controls cilium length. Acts as a regulator of protein stability by preventing ubiquitination of centrosomal proteins, such as CCP110 and tektins. Associates with the EDVP complex, preventing ubiquitination and degradation of CCP110. Promotes deubiquitination of tektin proteins (TEKT1, TEKT2, TEK3, TEKT4 and TEKT5) via its interaction with USP16 (By similarity)..
Function from UniProtKB (Q5JTW2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
38 statements
38 statements · 4 reference databases · Subject: CEP78 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
2 names
Resolves to: CEP78