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Proteins/UNIPROT:Q9Y278
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in GlcA2S-GlcNS. Unlike HS3ST1/3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate..
Function from UniProtKB (Q9Y278), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
8 statements
8 statements · 2 reference databases · Subject: HS3ST2 · Sources: Reactome, WikiPathways
2 reactions
MAM02086g+3'-phospho-5'-adenylyl sulfateproton+MAM02087g+adenosine 3',5'-bismonophosphate
Catalysed by HS3ST2 or HS3ST4 or HS3ST5
Reaction pageLeft to rightBalance undeterminableEC 2.8.2.23, 2.8.2.29Golgi apparatus
Human-GEM MAR07221CC BY 4.0Reference data
alpha-D-glucosaminyl-[heparan sulfate](n)+3'-phosphoadenylyl sulfate3-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n)+adenosine 3',5'-bisphosphate
5 names
Resolves to: HS3ST2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:15461CC BY 4.0Reference data