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Proteins/UNIPROT:Q9BRR9
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate..
Function from UniProtKB (Q9BRR9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
43 statements
43 statements · 3 reference databases · Subject: ARHGAP9 · Sources: gene ontology, Hetionet, Reactome
2 names
Resolves to: ARHGAP9