Proteins/UNIPROT:Q5T5U3

ARHGAP21

ProteinUNIPROT:Q5T5U3

Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions..

Function from UniProtKB (Q5T5U3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

26 statements

26 statements · 3 reference databases · Subject: ARHGAP21 · Sources: gene ontology, Hetionet, Reactome

Order

ADH7 covaries with ARHGAP21ProteinHetionet hetionet:covaries:131-57584Inferred only
HBZ covaries with ARHGAP21ProteinHetionet hetionet:covaries:3050-57584Inferred only
PKD1L3 covaries with ARHGAP21ProteinHetionet hetionet:covaries:342372-57584Inferred only
ARF1 interacts with ARHGAP21ProteinHetionet hetionet:interacts:375-57584Inferred only
ARRB2 interacts with ARHGAP21ProteinHetionet hetionet:interacts:409-57584Inferred only
CTNNA1 interacts with ARHGAP21ProteinHetionet hetionet:interacts:1495-57584Inferred only
PTK2B interacts with ARHGAP21ProteinHetionet hetionet:interacts:2185-57584Inferred only
RHOA interacts with ARHGAP21ProteinHetionet hetionet:interacts:387-57584Inferred only
ARHGAP21 participates in CDC42 GTPase cyclePathwayReactome R-HSA-9013148Inferred only
ARHGAP21 participates in RAC1 GTPase cyclePathwayReactome R-HSA-9013149Inferred only
ARHGAP21 participates in RAC2 GTPase cyclePathwayReactome R-HSA-9013404Inferred only
ARHGAP21 participates in RAC3 GTPase cyclePathwayReactome R-HSA-9013423Inferred only

Show the remaining 14

ARHGAP21 participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
ARHGAP21 participates in RHOA GTPase cyclePathwayReactome R-HSA-8980692Inferred only
ARHGAP21 participates in RHOB GTPase cyclePathwayReactome R-HSA-9013026Inferred only
ARHGAP21 participates in RHOC GTPase cyclePathwayReactome R-HSA-9013106Inferred only
ARHGAP21 participates in RHOD GTPase cyclePathwayReactome R-HSA-9013405Inferred only
ARHGAP21 participates in RHOF GTPase cyclePathwayReactome R-HSA-9035034Inferred only
ARHGAP21 participates in RHOG GTPase cyclePathwayReactome R-HSA-9013408Inferred only
ARHGAP21 participates in RHOJ GTPase cyclePathwayReactome R-HSA-9013409Inferred only
ARHGAP21 participates in RHOQ GTPase cyclePathwayReactome R-HSA-9013406Inferred only
ARHGAP21 participates in RND3 GTPase cyclePathwayReactome R-HSA-9696264Inferred only
ARHGAP21 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
ARHGAP21 participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
ARHGAP21 participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only
ARHGAP21 regulates regulation of small GTPase mediated signal transductionBiological processgene ontology Q5T5U3|GO:0051056Inferred only

Other names

4 names

Resolves to: ARHGAP21

Also called: ARHGAP10KIAA1424Rho GTPase-activating protein 10Rho-type GTPase-activating protein 21

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