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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
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Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Pathways

Names from Reactome and WikiPathways

pathways in the graph: 3,812

Filter pathways by name

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3,101–3,200 of 3,812, alphabetically

Sema4D induced cell migration and growth-cone collapseReactomeR-HSA-416572
Sema4D mediated inhibition of cell attachment and migrationReactomeR-HSA-416550
Semaphorin interactionsReactomeR-HSA-373755
semaxanib-resistant FLT3 mutantsReactomeR-HSA-9702577
Senescence and autophagy in cancerWikiPathways615

More of the reference layer

Biological processes
Anatomy
Cell types
Organisms
Materials
Regulatory assessments
Diseases

Evidence: Compounds · Outcomes · Papers · Search

Senescence associated secretory phenotype SASP

WikiPathways3391

Senescence-Associated Secretory Phenotype (SASP)ReactomeR-HSA-2559582

Sensing of DNA Double Strand BreaksReactomeR-HSA-5693548

Sensory PerceptionReactomeR-HSA-9709957

Sensory perception of salty tasteReactomeR-HSA-9730628

Sensory perception of sour tasteReactomeR-HSA-9729555

Sensory perception of sweet, bitter, and umami (glutamate) tasteReactomeR-HSA-9717207

Sensory perception of tasteReactomeR-HSA-9717189

Sensory processing of soundReactomeR-HSA-9659379

Sensory processing of sound by inner hair cells of the cochleaReactomeR-HSA-9662360

Sensory processing of sound by outer hair cells of the cochleaReactomeR-HSA-9662361

Separation of Sister ChromatidsReactomeR-HSA-2467813

Serine metabolismReactomeR-HSA-977347

Serine metabolismWikiPathways4688

Serotonin and anxietyWikiPathways3947

Serotonin and anxiety related eventsWikiPathways3944

Serotonin and melatonin biosynthesisReactomeR-HSA-209931

Serotonin clearance from the synaptic cleftReactomeR-HSA-380615

Serotonin HTR1 group and FOS pathwayWikiPathways722

Serotonin Neurotransmitter Release CycleReactomeR-HSA-181429

Serotonin receptor 2 and ELK SRF GATA4 signalingWikiPathways732

Serotonin receptor 4 6 7 and NR3C signalingWikiPathways734

Serotonin receptorsReactomeR-HSA-390666

Serotonin transporter activityWikiPathways1455

Severe congenital neutropenia type 4 (G6PC3)ReactomeR-HSA-3282872

SHANK3 pathway involved in Phelan McDermid syndromeWikiPathways5566

SHC-mediated cascade:FGFR1ReactomeR-HSA-5654688

SHC-mediated cascade:FGFR2ReactomeR-HSA-5654699

SHC-mediated cascade:FGFR3ReactomeR-HSA-5654704

SHC-mediated cascade:FGFR4ReactomeR-HSA-5654719

SHC-related events triggered by IGF1RReactomeR-HSA-2428933

SHC1 events in EGFR signalingReactomeR-HSA-180336

SHC1 events in ERBB2 signalingReactomeR-HSA-1250196

SHC1 events in ERBB4 signalingReactomeR-HSA-1250347

SHOC2 M1731 mutant abolishes MRAS complex functionReactomeR-HSA-9726840

Sialic acid metabolismReactomeR-HSA-4085001

Sickle cell diseaseWikiPathways5604

Signal amplificationReactomeR-HSA-392518

Signal attenuationReactomeR-HSA-74749

Signal regulatory protein family interactionsReactomeR-HSA-391160

Signal TransductionReactomeR-HSA-162582

Signal transduction by L1ReactomeR-HSA-445144

Signal transduction through IL1RWikiPathways4496

Signaling by activated point mutants of FGFR1ReactomeR-HSA-1839122

Signaling by activated point mutants of FGFR3ReactomeR-HSA-1839130

Signaling by ActivinReactomeR-HSA-1502540

Signaling by ALKReactomeR-HSA-201556

Signaling by ALK fusions and activated point mutantsReactomeR-HSA-9725370

Signaling by ALK in cancerReactomeR-HSA-9700206

Signaling by AMER1 mutantsReactomeR-HSA-4839748

Signaling by APC mutantsReactomeR-HSA-4839744

Signaling by AXIN mutantsReactomeR-HSA-4839735

Signaling by BMPReactomeR-HSA-201451

Signaling by BRAF and RAF1 fusionsReactomeR-HSA-6802952

Signaling by CSF1 (M-CSF) in myeloid cellsReactomeR-HSA-9680350

Signaling by CSF3 (G-CSF)ReactomeR-HSA-9674555

Signaling by CTNNB1 phospho-site mutantsReactomeR-HSA-4839743

Signaling by cytosolic FGFR1 fusion mutantsReactomeR-HSA-1839117

Signaling by cytosolic PDGFRA and PDGFRB fusion proteinsReactomeR-HSA-9673766

Signaling by EGFRReactomeR-HSA-177929

Signaling by EGFR in CancerReactomeR-HSA-1643713

Signaling by EGFRvIII in CancerReactomeR-HSA-5637812

Signaling by ERBB2ReactomeR-HSA-1227986

Signaling by ERBB2 ECD mutantsReactomeR-HSA-9665348

Signaling by ERBB2 in CancerReactomeR-HSA-1227990

Signaling by ERBB2 KD MutantsReactomeR-HSA-9664565

Signaling by ERBB2 TMD/JMD mutantsReactomeR-HSA-9665686

Signaling by ERBB4ReactomeR-HSA-1236394

Signaling by ErythropoietinReactomeR-HSA-9006335

Signaling by extracellular domain mutants of KITReactomeR-HSA-9680187

Signaling by FGFRReactomeR-HSA-190236

Signaling by FGFR in diseaseReactomeR-HSA-1226099

Signaling by FGFR1ReactomeR-HSA-5654736

Signaling by FGFR1 in diseaseReactomeR-HSA-5655302

Signaling by FGFR2ReactomeR-HSA-5654738

Signaling by FGFR2 amplification mutantsReactomeR-HSA-2023837

Signaling by FGFR2 fusionsReactomeR-HSA-8853333

Signaling by FGFR2 IIIa TMReactomeR-HSA-8851708

Signaling by FGFR2 in diseaseReactomeR-HSA-5655253

Signaling by FGFR3ReactomeR-HSA-5654741

Signaling by FGFR3 fusions in cancerReactomeR-HSA-8853334

Signaling by FGFR3 in diseaseReactomeR-HSA-5655332

Signaling by FGFR4ReactomeR-HSA-5654743

Signaling by FGFR4 in diseaseReactomeR-HSA-5655291

Signaling by FLT3 fusion proteinsReactomeR-HSA-9703465

Signaling by FLT3 ITD and TKD mutantsReactomeR-HSA-9703648

Signaling by GPCRReactomeR-HSA-372790

Signaling by GSK3beta mutantsReactomeR-HSA-5339716

Signaling by HedgehogReactomeR-HSA-5358351

Signaling by high-kinase activity BRAF mutantsReactomeR-HSA-6802948

Signaling by HippoReactomeR-HSA-2028269

Signaling by Insulin receptorReactomeR-HSA-74752

Signaling by InterleukinsReactomeR-HSA-449147

Signaling by juxtamembrane domain KIT mutantsReactomeR-HSA-9669935

Signaling by kinase domain mutants of KITReactomeR-HSA-9669933

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