Pathway
Synthesis of PE
De novo (Kennedy pathway) synthesis of phosphatidylethanolamine (PE) involves phosphorylation of ethanolamine (ETA) to phosphoethanolamine (PETA) followed by condensing with cytidine triphosphate (CTP) to form CDP-ethanolamine (CDP-ETA). Diacylglycerol (DAG) and CDP-ETA together then form PE. Alternatively, PE is formed when phosphatidylserine (PS) is decarboxylated by phosphatidylserine decarboxylase proenzyme (PISD).
REACT:R-HSA-1483213Reactome
What the reference databases state
Statements
13 statements
13 statements · 1 reference database · Subject: Synthesis of PE · Sources: Reactome
- CEPT1 participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- CHKA participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- CHKB participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- ETNK1 participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- ETNK2 participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- ETNPPL participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- LPIN1 participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- LPIN2 participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- LPIN3 participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- PCYT2 participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- PHOSPHO1 participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
- PISD participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only
Show the remaining 1
- SELENOI participates in Synthesis of PEProteinReactome R-HSA-1483213Inferred only