Pathway
SUMOylation of DNA methylation proteins
The known DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B) can be SUMOylated (reviewed in Xu et al. 2010, Denis et al. 2011). SUMOylation affects the catalytic activity of DNMT1 and the protein interactions of DNMT3A.
REACT:R-HSA-4655427Reactome
What the reference databases state
Statements
15 statements
15 statements · 1 reference database · Subject: SUMOylation of DNA methylation proteins · Sources: Reactome
- BMI1 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- CBX2 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- CBX4 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- CBX8 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- DNMT1 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- DNMT3A participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- DNMT3B participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- PCGF2 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- PHC1 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- PHC2 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- PHC3 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- RING1 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
Show the remaining 3
- RNF2 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- SUMO1 participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only
- UBE2I participates in SUMOylation of DNA methylation proteinsProteinReactome R-HSA-4655427Inferred only