Pathway
Dual Incision in GG-NER
Double incision at the damaged DNA strand excises the oligonucleotide that contains the lesion from the open bubble. The excised oligonucleotide is ~27-30 bases long. Incision 5' to the damage site, by ERCC1:ERCC4 endonuclease, precedes the incision 3' to the damage site by ERCC5 endonuclease.
REACT:R-HSA-5696400Reactome
What the reference databases state
Statements
41 statements
41 statements · 1 reference database · Subject: Dual Incision in GG-NER · Sources: Reactome
- CHD1L participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- CUL4A participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- CUL4B participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- DDB1 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- DDB2 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- ERCC1 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- ERCC2 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- ERCC3 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- ERCC4 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- ERCC5 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- GTF2H1 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- GTF2H2 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
Show the remaining 29
- GTF2H3 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- GTF2H4 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- GTF2H5 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- PARP1 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- PARP2 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- PCNA participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- POLD1 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- POLD2 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- POLD3 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- POLD4 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- POLE participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- POLE2 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- POLE3 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- POLE4 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- POLK participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- RBX1 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- RFC1 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- RFC2 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- RFC3 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- RFC4 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- RFC5 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- RPA1 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- RPA2 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- RPA3 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- RPS27A participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- UBA52 participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- UBB participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- UBC participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only
- XPA participates in Dual Incision in GG-NERProteinReactome R-HSA-5696400Inferred only