Endpoint
Birth weight
CAT:outcome/birth-weightreported in grams1 finding from 1 compound
What moved it
How to read these marks1 finding · 1 compound · by grade
| Compound | Direction | Findings | Best grade |
|---|---|---|---|
| all-cis-docosa-4,7,10,13,16,19-hexaenoic acid | up | 1 | Grade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence. |
Reported to move it
1 finding
all-cis-docosa-4,7,10,13,16,19-hexaenoic acid — increases
PreliminaryGrade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“In contrast, prenatal DHA supplementation significantly increased neonatal birth weight (mean difference [MD] = 72.51 g, 95% CI: 37.55-107.48), whereas no notable improvements were observed in head circumference, gestational age, birth length, or any of the assessed neurodevelopmental outcomes.”
Quoted verbatim from Impact of Omega-3 Fatty Acid Docosahexaenoic Acid Supplementation in Individuals During Pregnancy on Neurodevelopment and Growth of Offspring: Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- Pregnant women given prenatal DHA supplementation (meta-analysis pooling RCTs from 2001-2023, general population); birth weight measured in offspring
Effect 72.51 mean difference, 95% CI 37.55 to 107.48
Impact of Omega-3 Fatty Acid Docosahexaenoic Acid Supplementation in Individuals During Pregnancy on Neurodevelopment and Growth of Offspring: Systematic Review and Meta-Analysis.2026PMID:42494300Permalink
How it is measured
Weight of the infant recorded at birth, in grams, from the delivery or neonatal record.
Measured, not recorded
- Subject
- birth weight
- Measurements
- 2 measurements
- Recorded as a finding
- No
Show what was measured
birth weight
no effect, p = 0.54
There were no significant differences between DHA and placebo groups for mean birth weight (2750.6 ± 421.5 vs. 2768.2 ± 436.6 g, p = 0.54), birth length (47.3 ± 2.0 vs. 47.5 ± 2.0 cm, p = 0.13), or head circumference (33.7 ± 1.4 vs. 33.8 ± 1.4 cm, p = 0.15).
PMID:33668849 · one of two readings recorded this
birth weight
SMD = -0.348; 95% confidence interval [-0.777; 0.081]
A metaanalysis revealed that PME was associated with, among other findings, lower birth weight (SMD = -0.348; 95% confidence interval [-0.777; 0.081]), shorter body length (SMD= -0.198 [-0.348; -0.047]), and smaller head circumference (SMD= -0.479 [-1.047; 0.089]).
PMID:34140080 · one of two readings recorded this
Sources cited
1 paper
- Subject
- birth weight
- Findings
- 1
- Papers
- 1