Papers/PMID:26723196
Safety and pharmacokinetics of pravastatin used for the prevention of preeclampsia in high-risk pregnant women: a pilot randomized controlled trial.
American journal of obstetrics and gynecology2016The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
pravastatin — no detected effect on birth weight
Evidence strength: moderate.FindingNull result“Although pravastatin reduced maternal cholesterol concentrations, umbilical cord cholesterol concentrations and infant birthweight were not different between the groups.”
Quoted verbatim from Safety and pharmacokinetics of pravastatin used for the prevention of preeclampsia in high-risk pregnant women: a pilot randomized controlled trial.. - Study
- RCT
- Dose
- 10 mg daily until delivery
- Population
- Pregnant women at high risk of preeclampsia with singleton nonanomalous pregnancies, started at 12 to 16 weeks' gestation; pilot trial
Safety and pharmacokinetics of pravastatin used for the prevention of preeclampsia in high-risk pregnant women: a pilot randomized controlled trial.2016PMID:2672319610.1016/j.ajog.2015.12.038Permalink