4-aminobutanoate

Three steps

• O-4,8-dimethylnonanoyl-(R)-carnitineReach from here →
  1. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
  2. Carnitine Transport by Atb0
  3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal

  Catalysed by SLC6A12, SLC6A14, CRAT, CROTextracellular space, cytosol, peroxisomeOne of 5 routes

• N-tetradecanoylglycineReach from here →
  1. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)

  Catalysed by SLC6A12, SLC6A9, SLC6A14, GLYATL2extracellular space, cytosol

• N-eicosanoylglycinateReach from here →
  1. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)

  Catalysed by SLC6A12, SLC6A9, SLC6A14, BAATextracellular space, cytosol

• N-docosanoylglycineReach from here →
  1. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)

  Catalysed by SLC6A12, SLC6A9, SLC6A14, BAATextracellular space, cytosol

• N-hexacosanoylglycineReach from here →
  1. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)

  Catalysed by SLC6A12, SLC6A9, SLC6A14, BAATextracellular space, cytosol

• an N(2)-acyl-L-glutamineReach from here →
  1. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
  2. Transport of L-Glutamine by Atb0 Transporter
  3. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)

  Catalysed by SLC6A12, SLC6A14, GLYATL1B, GLYATL1extracellular space, cytosol

• taurochenodeoxycholateReach from here →
  1. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
  2. Neurotransmitter:Sodium Symporter (Nss) Tcdb:2.A.22.3.3
  3. 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:taurine N-choloyltransferase

  Catalysed by SLC6A12, SLC6A6, BAATextracellular space, cytosol, peroxisomeOne of 3 routes