hexadecanal

Three steps

• 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. hexadecanoate + NADH + 2 H(+) = hexadecanal + NAD(+) + H2O
  2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
  3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA

  Catalysed by ALDH3B1, ALDH3B2, ALDH3A2, SLC27A2 and 11 more

• 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
  1. hexadecanoate + NADH + 2 H(+) = hexadecanal + NAD(+) + H2O
  2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
  3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA

  Catalysed by ALDH3B1, ALDH3B2, ALDH3A2, SLC27A2 and 11 more

• 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. hexadecanoate + NADH + 2 H(+) = hexadecanal + NAD(+) + H2O
  2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
  3. a 2-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA

  Catalysed by ALDH3B1, ALDH3B2, ALDH3A2, SLC27A2 and 11 more

• N-hexadecanoylhexadecasphinganineReach from here →
  1. hexadecanoate + NADH + 2 H(+) = hexadecanal + NAD(+) + H2O
  2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
  3. hexadecasphinganine + hexadecanoyl-CoA = N-hexadecanoylhexadecasphinganine + CoA + H(+)

  Catalysed by ALDH3B1, ALDH3B2, ALDH3A2, SLC27A2 and 12 more

• 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-hexadecanoyl-sn-glycero-3-phospho]-glycerolReach from here →
  1. hexadecanoate + NADH + 2 H(+) = hexadecanal + NAD(+) + H2O
  2. hexadecanoate + ATP + CoA = hexadecanoyl-CoA + AMP + diphosphate
  3. 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA = 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA

  Catalysed by ALDH3B1, ALDH3B2, ALDH3A2, SLC27A2 and 11 more

• beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enineReach from here →
  1. hexadecanoate + NADH + 2 H(+) = hexadecanal + NAD(+) + H2O
  2. N-hexadecanoylsphing-4-enine + H2O = sphing-4-enine + hexadecanoate
  3. beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-hexadecanoylsphing-4-enine

  Catalysed by ALDH3B1, ALDH3B2, ALDH3A2, NAAA and 4 more

• N-(dodecanoyl)-sphinganineReach from here →
  1. Sphinganine-1-phosphate pamlmitaldehyde-lyase
  2. sphinganine 1-phosphate + H2O = sphinganine + phosphate
  3. N-(dodecanoyl)-sphinganine + H2O = dodecanoate + sphinganine

  Catalysed by SGPL1, SGPP2, SGPP1, ASAH1cytosol